Reactive oxygen species levels are independent of sperm concentration, motility, and abstinence in a normal, healthy, proven fertile man: a longitudinal study.

نویسندگان

  • Nisarg R Desai
  • Reda Mahfouz
  • Rakesh Sharma
  • Sajal Gupta
  • Ashok Agarwal
چکیده

In a longitudinal study over a period of 21 months, we demonstrated that seminal reactive oxygen species (ROS) levels are independent of sperm concentration, motility, and abstinence duration within a healthy sperm donor, although some variations were observed in ROS levels. We suggest that fluctuation in seminal ROS values may be related to physiologic or transient changes in spermatogenesis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P-16: Antiapoptotic and Antioxidant Effect of Insulin Like Factor-3 on Sperm of Fertile Men After Cryopreservation

Background Freezing process has destructive effect on different functions of sperm. Therefore, sperm motility was reduced and apoptosis and DNA damage and also levels of reactive oxygen species (ROS) were increased. Insulin-like factor-3 (INSL3) is a member of Relaxin family and directly affects on spermatogenesis and also plays a protective role against apoptosis. Therefore, with due regard to...

متن کامل

P-21: Study of The Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers in Spermatozoa of Patients with Asthenospermia

Background: Oxidative stress and decreased antioxidant levels have been projected as a potential factors involved in the pathophysiology of diverse male infertility types, including asthenospermia. The generation of reactive oxygen species (ROS) in the male reproductive tract has become an actual concern because of their probable noxious effects, at high levels, on physical properties of sperm ...

متن کامل

Novel association between sperm reactive oxygen species production, sperm morphological defects, and the sperm deformity index.

OBJECTIVE To examine the relationship between sperm reactive oxygen species (ROS) production and sperm morphology in a group of infertile men and healthy fertile donors. DESIGN A prospective clinical study. SETTING Male infertility clinic, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, and the Reproductive Medicine Unit, Liverpool Women's Hospital, United K...

متن کامل

Effect of vitamin D on apoptotic marker, reactive oxygen species and human sperm parameters during the process of cryopreservation

Objective(s): Sperm cryopreservation plays an undeniable role in assisted reproductive technology. However, this process significantly reduces the motility, viability, morphology and nuclear integrity of sperm. Reasons of these changes were oxidative stress and apoptosis. The aim of this study was to evaluate the influence of vitamin D on the survival and integrity of ...

متن کامل

Effect of smoking on sperm vitality, DNA integrity, seminal oxidative stress, zinc in fertile men.

OBJECTIVE To assess the effect of smoking on sperm vitality, sperm DNA integrity, semen reactive oxygen species, and zinc levels in fertile men. METHODS One-hundred sixty men were investigated. They were divided into 2 equal groups: healthy fertile nonsmokers and healthy fertile smokers. They were subjected to history taking, clinical examination, and semen analysis. In their semen, sperm hyp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Fertility and sterility

دوره 94 4  شماره 

صفحات  -

تاریخ انتشار 2010